Davante Adams increased his TD count for the season to half a dozen.
Travis Hunter scored his maiden professional score but it was just a solace as the Rams brushed off time zone issues to claim a 35-7 triumph over the Jacksonville Jaguars at Wembley Stadium.
Los Angeles did not arrive in the Britain until Saturday AM - the prior day to the final game of this campaign's UK games, which was the 43rd NFL contest to be staged in the English capital.
This marked the most delayed any squad has traveled for an NFL game in London, while the Jacksonville, who also entered the contest with a four and two standing, had been in London since last Tuesday.
But the LA team raced into a 21-0 halftime lead before coasting through the latter part, with veteran receiver Davante Adams registering a hat-trick of touchdowns as the team ended up with five in total.
Hunter guaranteed the opponents evaded a blanking with nine minutes left, helping to narrow the margin to 28-7, but it did not diminish an dominant victory by the Rams, who have been predicted to be in championship contention again this season having last claimed the NFL's championship game in two years ago.
